Journals Watch 2002

This section features a regularly updated list of recently published articles relevant to nurse prescribing.

Abstracts of the papers are included and users are encouraged to submit their views about published papers through the feedback section.

Please note: In this section of the website we aim to cover articles on areas where nurses do prescribe. However, not all the treatments or appliances mentioned are prescribable by nurses. For that reason, nurses should check the up-to-date versions of the Nurse Prescribers’ Formulary for District Nurses and Health Visitors (NPF) and the Nurse Prescribers’ Extended Formulary (NPEF) and Drug tariff if they are in any doubt. Alternatively contact your Regional Nurse Prescribing Lead for clarification.


Minor Injuries
Click on the article title below to read the summaries. 

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  • Ibuprofen gel effective in soft tissue injuries

Machen J and Whitefield M. Efficacy of a propietary ibuprofen gel in soft tissue injuries: a randomised, double-blind, placebo-controlled study. Int J Clin Pract 2002: 56(2): 102-106

In this study of 85 patients with recent soft tissue injuries, a proprietary topical formulation of ibuprofen 5% gel (IbugelTM) was found to have advantages over placebo in treating the injuries.

Topical NSAIDS offer a potential advantage over oral NSAIDS as the smaller resultant drug concentration should reduce the risk of gastrointestinal toxicity.

The patients in this study gently massaged the gel (active or placebo) into their injury until absorbed three times a day for a maximum of seven days. ‘Clinically meaningful relief’ of pain and interference with physical activity measures were pre-defined.

Patients in the active group reported achieving clinically significant reductions in pain and interference with physical activity earlier than those in the placebo group. By day 7, 75% of patients in the active group had a clinically significant reduction in pain compared with 39% of those in the placebo group. There was a strong placebo effect for pain reduction, however, perhaps partly reflecting a failure in ‘minimal rub’ technique. Both treatments were well tolerated.